Ser935/total full-length LRRK2 varied ∼1.5-fold between donors (Figure 4C), while there was ∼3-fold variance between total Rab10 levels (Figure 4D) with no significant differences between healthy controls, sporadic Parkinson's disease and heterozygous G2019S LRRK2 mutation carriers for any of these analysis (Figure 4). This evidence concerns the gene LRRK2 and Parkinson disease.