CLEC5A and atherosclerosis: Therefore, MDL-1 is predicted to cause inflammatory lesional macrophage accumulation in the context of early atherosclerosis and these discoveries provide a novel macrophage receptor biomarker regarding to the relationship between its level and atherosclerotic plaque progression and link abnormal lipid level to macrophage survival and accumulation, which might further aggravate plaque foam cell burden and promote atherosclerosis progression.