PRTN3 and rheumatoid arthritis: 8072 for ACPA-positive patients with RA (P < 0.0001; 92% specificity and 67% sensitivity), whereas FDRs showed AUCs of 0.9350 (P < 0.0001; 92% specificity and 83% sensitivity) compared with HCs and 0.7507 (P < 0.001; 71% specificity and 78% sensitivity) compared with patients with RA.