FCRL3 and obesity due to melanocortin 4 receptor deficiency: Globally, we found that the development of an extreme cardiometabolic phenotype can be predicted by common and rare variants in BAD and FCRL3. The presence of dyslipidemia in cALL survivors is influenced by common variants in OGFOD3 and APOB and by common and rare variants in BAD. Obesity was predicted by a common variant in BAD and insulin resistance was associated with a common variant in SERPINA6. Pre-HTN was related to survivors’ gender as being a female was found protective for this complication.