ENO2 and neoplasm: Immunohistochemically, tumor cells were positive for neuron-specific enolase (NSE, Fig. 2b), synaptophysin (Syn, Fig. 2c), cytokine 56 (CD56, Fig. 2d), cytokine 99 (CD99), P63 (++), P16, P53 (90%+), and Ki-67 (90%+).