Ozkan et al found that the rate of chronic pulmonary damage was 5 times higher in pediatric age groups with IgGScD than those with low IgA.46 It has been reported that bronchiectasis may already be present in as many as 10% of IgGScD pediatric patients at diagnosis.43 In a study of 350 adult IgGScD patients, 29% had asthma, 9% had asthma combined with chronic obstructive pulmonary disease (COPD), and 9% had COPD alone.48 This evidence concerns the gene CD79A and bronchiectasis.