SLC25A3 and Friedreich ataxia: The expression of eight genes belonging to the SLC25 family are significantly changed in FRDA fibroblasts, including the most significantly changed SLC gene in our analysis, SLC25A3. Deleterious mutations in SLC25A3 are implicated in mitochondrial phosphate-carrier deficiency disorder (OMIM #610773), which, like FRDA, features cardiomyopathy as a major symptom (Mayr et al., 2007).