A total of 25% of patients with GATA2 mutations in the above cohort developed thrombotic events, such as DVT, pulmonary embolism, portal vein thrombosis and catheter-related thrombosis (Spinner et al., 2014), possibly because GATA2 deficiency in the endothelium causes coagulopathy. The gene discussed is GATA2; the disease is Portal vein thrombosis.