HLA-DRB1 and type 1 diabetes mellitus: HLA-DRB1*0401-DQB1*0302 and HLA-DRB1*0301-DQB1*0201 have been associated with T1D susceptibility whereas the haplotypes HLA-DRB1*1501 and HLA-DQA1*0102-DQB1*0602 confer resistance (48).