The expression of FAK, an enzyme involved in the mechanical signaling associated with skeletal muscle hypertrophy (Flück et al., 1999; Klossner et al., 2009), was increased in hypertrophied soleus and EDL muscles after 7 days of overload when animals were previously submitted to 30 days of diabetes (Fortes et al., 2015). Here, PTK2 is linked to diabetes mellitus.