In the current study, according to the available evidence and our recent study on the plasma expression of lncRNAs25, we detected the expression levels of four lncRNAs (GAS5, lnc-DC, linc0597 and linc0949) in the PBMCs from SLE patients at the first stage, and investigated their clinical associations. The gene discussed is DCX; the disease is systemic lupus erythematosus.