NFKB1 and vitamin D deficiency: This randomized placebo-controlled trial examined the effect of oral cholecalciferol (100,000 IU bolus followed by 4,000 IU daily) supplementation for 16 weeks on pro- and anti-inflammatory markers and NFκB activity in overweight or obese but otherwise healthy individuals with vitamin D deficiency (25(OH)D ≤ 50 nmol/L).