CD8A and neoplasm: To better track the fate of tumor-specific CD8+ T cells in this model, and to evaluate another clinically relevant immunotherapy approach, we resorted to adoptive transfer of P1A-specific CD8+ T cells isolated from mice transgenic for the anti-P1A T-cell receptor (TCR) (TCRP1A mice in the Rag1−/− B10.D2 background)10.