REN and basal cell carcinoma: As a result, 24 KEGG pathways were enriched for upregulated DEGs, including Renin-angiotensin system (e.g., Agt, angiotensinogen), Renin secretion (e.g., Agt), and Wnt signaling pathway (e.g., Dkk1), while 16 pathways were for downregulated DEGs, including basal cell carcinoma (e.g., Lef1) (Table 2).