As a result, 24 KEGG pathways were enriched for upregulated DEGs, including Renin-angiotensin system (e.g., Agt, angiotensinogen), Renin secretion (e.g., Agt), and Wnt signaling pathway (e.g., Dkk1), while 16 pathways were for downregulated DEGs, including basal cell carcinoma (e.g., Lef1) (Table 2). The gene discussed is LEF1; the disease is basal cell carcinoma.