INS and diabetes mellitus: Animals with diabetes had higher fasting blood glucose (9.9 ± 0.6 mmol/l vs. 4.6 ± 0.3 mmol/l, p < 0.001) and higher insulin concentrations (7.7 ± 1.6 μIU/ml vs. 0.7 ± 0.3 μIU/ml, p < 0.001) than animals without diabetes.