In respect of the percentage of positive breast carcinoma cases for leptin immunoexpression, our results are in line with those of Garofalo and associates [33], Fiorio and coworkers [36], Jarde and associates [37] and Jeong team [39] who detected leptin immunoexpression in 86.4%, 79.6%, 79.6% and 83% of breast carcinomas respectively, but with different immunoreactivity levels; and varied from those of Ishikawa, Kitayama and Nagawa [31], Caldefie-Chezet and associates [32], Kim [38] and Colbert and colleagues [40]. The gene discussed is LEP; the disease is breast carcinoma.