Among the seven selected proteins, only glucose-regulated protein (GRP) 78 showed an HCMV-induced increase in protein expression (1.88 fold), whereas CD44 (2.00 fold), caveolin-1 (1.92 fold), catenin delta-1 (δ-catenin) (1.79 fold), CD59 (1.75 fold), CD81 (1.61 fold) and CD98 (1.56 fold), were downmodulated by HCMV infection (Fig 1G). Here, CD81 is linked to cytomegalovirus infection.