Pathogenic variants in many other genes, including protein components of the sarcomere (e.g. TNNT2, TPM1), Z-disk (e.g. TCAP, MYPN, NEXN), cytoskeleton (e.g. DES, VCL), desmosome (e.g. DSP), and RNA-binding proteins (e.g. RBM20), have been reported in DCM cohorts. The gene discussed is RBM20; the disease is familial dilated cardiomyopathy.