It can transduce IL17 signaling, such as the activation of extracellular-regulated protein kinases (ERK), p38, and nuclear transcription factor κB (NF-κB) [31] to impact on cancer, since mitogen-activated protein kinase (MAPK) and NF-κB signals have important roles at the molecular mechanisms of anticancer [32]. Here, NFKB1 is linked to cancer.