DOK3 and colorectal cancer: Many researchers have demonstrated that miRNA binding site SNPs would influence the development of cancer: Song et al. [24] found that a miR-29c binding site genetic variant in the 3′-UTR of LAMTOR3 gene was associated with GC risk; Kang et al. [25] indicated that SNPs in 3′-UTR of docking protein 3 gene (DOK3) may affect the expression of DOK3, then impact on colorectal cancer by altering the miR-370 binding efficiency.