Previous research has also implicated EGR-2 in both the differentiation and myelination of nerve cells in mice43, and mutations within the EGR-2 gene have been associated with peripheral neuropathies, including Charcot-Marie-Tooth type 1, Dejerine-Sottas syndrome and congenital hypomyelinating neuropathy44. This evidence concerns the gene EGR2 and Dejerine-Sottas syndrome.