NFKB1 and posterior cortical atrophy: Given the role of NF-κB in PCa, and our previous findings that hSef-a can inhibit NF-κB activation in response to pro-inflammatory cytokines17, we next examined whether hSef-b can also inhibit NF-κB in TRAMP C2 cells using hSef-a as a positive control for NF-κB inhibition.