MMP9 and posterior cortical atrophy: To gain further insight into the mechanism by which hSef-b inhibits PCa growth and neovascularization we analyzed the expression levels of FGF2 and matrix metalloproteinase-9 (MMP-9) in tumors transfected with the control (N = 3) or the hSef-b (N = 4) plasmid by RT-PCR.