LGALS7 and cancer: The mechanisms responsible for such constitutive expression of gal-7 intracellularly, however, remain largely unknown although it is logical to assume that gal-7 in cancer cells is regulated, at least in part, at the transcriptional level via DNA methylation and the implication of specific transcription factors, such as mutant p53, Nf-kB, and the CCAAT/enhancer-binding protein beta-2 isoform (CEBPβ-2) [8–10].