To investigate the role of CXC chemokines and its receptor in BD patients, we measured levels of CXC chemokines (CXCL1, CXCL8, CXCL9, CXCL10, CXCL12, CXCL13 and CXCL16) and compared them with disease activity and clinical manifestations. This evidence concerns the gene CXCL1 and Behcet disease.