The CXCL10/CXCR3 and CXCL13/CXCR5 axes are associated with disease activity in several autoimmune diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and adult onset Still’s disease8–12. This evidence concerns the gene CXCR5 and systemic lupus erythematosus.