Interestingly, the second most abundant phage clone overrepresented in the cancer mice was CGEKRTRGC (Fig. 1c), a clone that was previously identified23 together with LyP-1 (CGNKRTRGC), a peptide known to target the p32 protein overexpressed on the surface of TAMs and tumor lymphatic endothelial cells12. This evidence concerns the gene PTPN22 and cancer.