TARDBP and neuroblastoma: When N2a (or SH-SY5Y neuroblastoma) cells were transiently transfected to express an aggregation-prone C-terminal fragment of TDP-43 fused to GFP (TDP-43CTF-GFP), which forms aggregates with structural similarity to those in human post-mortem tissue and that is widely used as a tool to study TDP-43 aggregation [33], they developed cytoplasmic inclusions readily detected by confocal microscopy.