To screen the miRNAs that are dysregulated in BRAF-mutant tumors, we then divided 64 tumor samples from the entire cohort into two sets as follows: a screening set (15 KRAS/BRAF-wild-type tumors and 15 BRAF-mutant tumors from the TUH and NCCH cohort) and a validation set (30 KRAS/BRAF-wild type tumors and four BRAF-mutant tumors from the TUH cohort) (Table 1). This evidence concerns the gene BRAF and neoplasm.