As our study was performed using human cell lines, in order to confirm the tight regulation of DAO and DAOA assumed in the human central nervous system (CNS), modeling the interactions between DAO and DAOA proteins in schizophrenia patient specific neuroglial culture i.e., hiPSC derived neurons and glia co-cultures and comparing them to healthy control derived neuroglial cultures might further help in settling the debate of DAOA effect on DAO and NMDA receptor activity. Here, DAO is linked to schizophrenia.