DAO and DAOA genes are alleged to be involved in pathophysiology of neuropsychiatric disorders such as schizophrenia and bipolar disorder (Detera-Wadleigh and McMahon, 2006; Allen et al., 2008; Prata et al., 2008; Gatt et al., 2015), but the interactions between these genes remains unclear to date. This evidence concerns the gene DAOA and bipolar disorder.