MET and cancer: For example, Chaffer et al. used a series of bladder cancer cell lines to study the role MET in the metastasis cascade and found that reversion to epithelial characteristics in a mesenchymal-like cancer cell line, i.e., regaining an epithelial phenotype, was favorable in the latter stages of the metastatic cascade; this finding confirmed the suspected role of MET in secondary cancer growth [81, 82].