INS and neoplasm: Accordingly, in an attempt to unequivocally elucidate the association between BCa and glucose/insulin metabolism, by more accurately assessing IR, and by appropriately stratifying the patients by BMI and menopausal state, we have implemented a prospective study including 148 women with suspect of non-familial, sporadic BCa in whom we measured glucose, insulin, glycohemoglobin, and other IR-related and tumor-derived markers, as well as glucose/insulin levels during the OGTT.