CDH1 and neoplasm: However, negative E-cadherin expression was correlated with FIGO stage (I/II vs. III/IV, pooled OR = 0.42, 95% CI = 0.31–0.57, p < 0.001), tumor grade (1/2 vs. 3, pooled OR = 0.48, 95% CI = 0.34–0.67, p < 0.001), metastasis (Absent vs. Present, pooled OR = 0.13, 95% CI = 0.07–0.26, p < 0.001) and recurrence (Absent vs. Present, pooled OR = 0.48, 95% CI = 0.29–0.79, p < 0.001).