CHERP and cancer: Although some studies performed in mammalian cells have elucidated some functions of CHERP, such as controlling intracellular Ca2+ mobilization and cell growth, acting as part of splicing factors and participating in post-transcriptional regulation of splicing variants in Ca(2+) signaling pathways, etc. [5, 10, 11], there has been little progress in understanding the role of CHERP in humans, especially in human cancer cells.