In the external validation cohort of 107 patients reported on TCGA database (2015), who had tumor recurrence records, the Kaplan-Meier estimates of disease-free survival (DFS) revealed that high KDM4A expression was significantly associated with the time of disease recurrence and progress (log-rank, P < .05), and consequently, with poor survival (Figure 3). Here, KDM4A is linked to neoplasm.