Notably, there were obvious differences in the expression levels of both proteins between cancerous and adjacent normal tissues (Figure 3B and 3D); the positive expression rate of YAP1 (86.7%, 104/120) and HSPC111 (40%, 48/120) in GC samples was significantly higher than that in normal gastric samples (66.7%, 20/30 and 16.7%, 5/30; P = 0.015 and P = 0.019, respectively). The gene discussed is YAP1; the disease is gastric cancer.