IL6 and metabolic dysfunction-associated steatohepatitis: The serum level of IL-6 was significantly higher in the NASH-HFD group (113.7 ± 10.8 pg/mL) compared to the NASH-STD group (58.4 ± 4.2 pg/mL); however, it was not detected in the serum of HL-mice, regardless of whether they were fed HFD or STD (Figure 3).