The following constellations were frequently observed (Fig 4A–4C): for 79 highly correlating probe sets (56 genes), only one tumor displayed high copy number gain as illustrated for the example of CDCA4 (Fig 4A); for 29 highly correlating probe sets (14 genes), more than ten tumors showed high copy number gain, exemplified by in Fig 4B (ECCC = 0.771); and for 46 highly correlating probe sets (40 genes), no tumor demonstrated high copy number gain (Fig 4C). Here, CDCA4 is linked to neoplasm.