Other secondary outcomes included quality of life, anthropometric measures (e.g., lean body mass, grip strength, DEXA), pathology (e.g., reactive oxygen species, glutathione peroxidase, superoxide dismutase, pro-inflammatory cytokines and C-reactive protein), physical function, depression and mood scales, measures of peripheral neuropathy and treatment response (e.g., complete remission, partial response, minimal response). This evidence concerns the gene CRP and depressive symptom measurement.