Interestingly, miR-210 does not target major hiscompatability class I (MHC class I) molecule genes or any other gene associated with cell recognition, and it has no effect on hypoxia transcription factors such as HIF1α or HIF2α. Contrarily, miR-210 inhibition of PTPN1, HOXA1, and TP53I11 has been showed to have a great influence on Cytoxic T Lymphocytes (CTL) lysis: miR-210 knock down restores the sensitivity to CTL lysis by tumor cells, likely through the stimulation of TNF-α, IL-6, and IFN-β. Here, TNF is linked to neoplasm.