In ovarian carcinoma, VM correlates with the immunohistochemical detection of ALDH1, Kisspeptin (KiSS-1), and Metastasis associated in colon cancer-1 (MACC1), which are used to predict metastasis and prognosis, and VM proved to be a prognostic marker, as well as a potential target to treat epithelial ovarian carcinoma [346]. The gene discussed is KISS1; the disease is cancer.