The oncogenic lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is implicated in tumor angiogenesis and also in VM by upregulating the expression of VE-cadherin, β-catenin, MMP-2, MMP-9, MMP-14, p-ERK, p-FAK, and p-paxillin [336], by upregulating N-cadherin and fibronectin, and by suppressing E-cadherin [113]. This evidence concerns the gene CDH5 and neoplasm.