CSF2 and myeloid sarcoma: There was an intention to search for the signaling molecule responsible for the propagation of granulocyte macrophage colony-stimulating factor (GM-CSF) memory B cells, and it was found that the signal transducer and activator of transcription 5/6 (STAT5/6)-regulated mechanistic pathway is upregulated in untreated MS patients, and this also reciprocally regulates the IL-10 secretion [37].