There were no variants in any of the known dystonia genes (TOR1A, TUBB4A, THAP1, CIZ1, ANO3, GNAL. SCGE, GCH1, TH, TITF1, TAF1, PRKRA, ATP1A3, SLC63, ADCY5) that survived filtration that removed alleles present in public databases at a frequency > 2%, in any affected individual. The gene discussed is CIZ1; the disease is Dystonia.