MAPK8 and type 2 diabetes mellitus: The protein level of SOCS-3 and JNK was obviously higher in the T2DM group than that from the normal group (p < 0.05 and p < 0.01), but it was decreased obviously in all treatment groups compared with that from the T2DM group (p < 0.05 and p < 0.01), and the protein level decreased with the increasing dosage of MCE (Figure 7).