Of note, patients in the liver dysfunction group retained significantly higher levels of serum cytokines IL-2R, IL-6, IL-10, and TNF-α, compared with those in the matched control group (p = 0.003, p = 0.022, p = 0.045, and p < 0.001, resp.; Figure 2 and Table 1S) and healthy volunteers (all p < 0.001; Figure 2). Here, TNF is linked to Decreased liver function.