In model b, with further adjustment for BMI, WC, GGT (log-transformed), TG, HDL–C, and HOMA–IR, the SHBG related ORs for presence of both MS and NAFLD decreased slightly (P = 0.001 for MS, P < 0.001 for NAFLD). This evidence concerns the gene SHBG and metabolic dysfunction-associated steatotic liver disease.