PDHA1 and breast neoplasm: Specific to the LC-MS/MS phosphoproteomics dataset (Fig. 8A), the upregulated pSTY data in mouse breast tumor tissue includes S293 on Pdha1 (Pyruvate dehydrogenase E1 component subunit alpha) which regulates the activity of the enzyme and further induces the activity of upregulated sites (S232, S295)51.