TUBA1A and microcephaly: Initial reports focused on the presence of other specific abnormalities found in TUBA1A-related lissencephalies, and these consist of a unique combination of microcephaly, pachygyria, complete or partial agenesis of the corpus callosum, cerebellar hypoplasia involving mainly the inferior vermis, brain stem hypoplasia, disorganization of the hippocampus, and dysmorphism of the basal ganglia [16].