Pterostilbene inhibited tumor in human hepatocellular carcinoma cells by suppressing various signal transduction pathways [33], including mitogen-activated protein kinase (MAPK), NF-κB, matrix metalloproteinase-9 (MMP-9), expression of vascular endothelial growth factor (VEGF) and AP-1 [34]. The gene discussed is MMP9; the disease is hepatocellular carcinoma.