PTEN and Familial prostate cancer: Recent studies showed that pterostilbene could down-regulate the phosphatase and tensin homolog (PTEN)-targeting members of the oncogenic miR-17 family, which were over-expressed in prostate cancer, and functionally validated the miRNA-mediated ability of resveratrol and pterostilbene to rescue the tumor suppressor activity of PTEN as therapeutic strategy [38].