Recent data suggest approximately 10% of young or familial TNBC patients with no BRCA1 or BRCA2 mutation carry inherited deleterious mutations in other breast cancer predisposition genes, particularly in genes involved in HRR such as PALB2, BARD1, RAD51C, RAD51D, and BRIP1 [8-10]. The gene discussed is BRCA2; the disease is breast carcinoma.