Recent data suggest approximately 10% of young or familial TNBC patients with no BRCA1 or BRCA2 mutation carry inherited deleterious mutations in other breast cancer predisposition genes, particularly in genes involved in HRR such as PALB2, BARD1, RAD51C, RAD51D, and BRIP1 [8-10]. This evidence concerns the gene BRCA1 and breast cancer.