PLA2G6 and Parkinson disease: Our results showed that in contrast to wild-type PLA2G6, PARK 14 mutant (D331Y), (G517C), (T572I), (R632W), (N659S) or (R741Q) PLA2G6 failed to prevent mitochondrial dysfunction, reactive oxygen species (ROS) production and activation of mitochondrial apoptotic pathway in rotenone-induced cellular model of PD.