We next examined whether SAMe, MTA and miR-34a/b influence the expression of these MAT genes and proteins in 22Rv-1 (human prostate cancer cell line) and MIA PaCa-2 (human pancreatic cancer cell line), which express moderate levels of these proteins as compared to multiple other prostate and pancreatic cancer cell lines (Figure 7). Here, MAT1A is linked to prostate carcinoma.