Previous studies have shown that expression of CYTOR was increased in gastric cancer [26], renal cell carcinoma (RCC) [27] and gallbladder cancer [28], as compared to paired non-neoplastic tissues, high CYTOR expression was positively associated with lymph node metastasis, high TNM stage, and poor over survival [9]. This evidence concerns the gene CYTOR and hereditary clear cell renal cell carcinoma.