As shown in Figure 6A-6B, within glioma samples of TCGA along with LGG subtypes, the overall survival of low PVT1 expression group was significantly better than that of high expression group in glioma patients who received chemotherapy (P <0.0001 and P =0.0004) or radiotherapy (P <0.0001 and P =0.0005). The gene discussed is PVT1; the disease is central nervous system cancer.